经过评估,专家小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase; EC 3.1.1.3) is produced with the non-genetically modified Rhizopus arrhizus strain AE-TL(B) by Amano Enzyme Inc. A safety e
valuation of this food enzyme was made previously, in which EFSA co
ncluded that this food enzyme did not give rise to safety co
ncerns when used in two food manufacturing processes. Subsequently, the applicant requested to extend its use to include four additio
nal processes and to revise the use levels. In this assessment, EFSA updat
ed the safety e
valuation of this food enzyme when used in a total of six food manufacturing processes. As the food enzyme-total organic solids (TOS) are removed from one food manufacturing process, the dietary exposure to the food enzyme-TOS was estimated o
nly for the remaining five processes. Dietary exposure was calculated to be up to 0.086 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level reported in the previous opinion (1960 mg TOS/kg bw per day, the highest dose tested), the Panel derived a margin of exposure of at least 22,791. ba
sed on the data provided for the previous e
valuation and the revised margin of exposure in the present e
valuation, the Panel co
ncluded that this food enzyme does not give rise to safety co
ncerns under the revised intended co
nditions of use.
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