经过评估,专家小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
The food enzyme oryzin (EC 3.4.21.63) is produced with the non-genetically modified Aspergillus ochraceus strain AE-P by Amano Enzyme Inc. A safety e
valuation of this food enzyme was made previously, in which EFSA co
ncluded that this food enzyme did not give rise to safety co
ncerns when used in nine food manufacturing processes. Subsequently, the applicant has requested to extend its use to one additio
nal process, to withdraw two food processes and to revise the use levels. In this assessment, EFSA updated the safety e
valuation of this food enzyme when used in a total of eight food manufacturing processes. The dietary exposure to the food enzyme-total organic solids (TOS) was calculated to be up to 0.354 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level reported in the previous opinion (1862 mg TOS/kg bw per day, the highest dose tested), the Panel derived a margin of exposure of at least 5260. ba
sed on the data provided for the previous e
valuation and the revised margin of exposure in the present e
valuation, the Panel co
ncluded that this food enzyme does not give rise to safety co
ncerns under the revised intended co
nditions of use.
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