经过评估,专家小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
The food enzyme glucan 1,4-α-glucosidase (4-α-d-glucan glucohydrolase; EC 3.2.1.3) is produced with the non-genetically modified Rhizopus arrhizus strain AE-G by Amano Enzyme Inc. A safety e
valuation of this food enzyme was made previously, in which EFSA co
ncluded that this food enzyme did not give rise to safety co
ncerns when used in one food manufacturing process. Subsequently, the applicant requested to extend its use to nine additio
nal processes and revised the use levels. In this assessment, EFSA updat
ed the safety e
valuation of this food enzyme for uses in a total of 10 food manufacturing processes. As the food enzyme–total organic solids (TOS) is removed from the final foods in two food manufacturing processes, the dietary exposure to the food enzyme–TOS was estimated o
nly for the remaining eight processes. Dietary exposure was up to 0.424 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (1868 mg TOS/kg bw per day, the highest dose tested), the Panel derived a margin of exposure of at least 4406. ba
sed on the data provided for the previous e
valuation and the margin of exposure revised in the present e
valuation, the Panel co
ncluded that this food enzyme does not give rise to safety co
ncerns under the revised intended co
nditions of use.
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